Sildenafil, an ingredient in Kamagra tablets, works on the penis' erectile tissue to increase blood flow, which results in an erection. The erectile tissue of the penis releases nitric oxide during sexual stimulation, activating the guanylate cyclase enzyme. An erection is brought on by this enzyme's elevation of the chemical cyclic guanosine monophosphate, which relaxes the blood vessels in the penis and permits blood to fill the spongy erectile tissues. An erection can be lost when phosphodiesterase type 5, another enzyme, breaks down cGMP and prevents blood flow to the penis. By preventing PDE5 from acting, kamagra store treat erectile dysfunction by enabling sexual stimulation to naturally trigger the cGMP mechanism, which is necessary for getting and keeping an erection.
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